Which Papilloma Ointment is the Most Effective and Has the Fewest Side Effects?

Papilloma ointment is a local drug that has an antiviral and anti-inflammatory effect. Some ointments for benign neoplasms have an unfavorable side effect profile. The effectiveness of drug therapy depends on the correct choice of drug.

ointment for papillomas

General information about pathology

Genital papillomas are benign neoplasms that are caused by viral diseases of different etiologies. Often, genital warts do not hurt. In a third of victims, they disappear after a few months.

Sometimes, small papules can itch, bleed, and hurt during intercourse. Victims feel at a disadvantage in their sex lives. Many also consider their genital warts to be a cosmetic problem. They are ashamed and want to get rid of them as soon as possible.

There are many ways to treat skin lesions. Therapy depends on which part of the body the genital warts are located. Another concern is whether there are other sexually transmitted diseases such as yeast infections, genital herpes, HIV or chlamydia.

In the case of growth of the lining of the vagina or opening of the urethra, for example, treatment with trichloroacetic acid can kill the warts. However, in flat warts, the doctor usually resorts to surgical interventions.

No method guarantees that genital warts (Condylomata acuminata) will disappear forever. Because the immune system doesn't always completely eliminate the human papillomavirus that causes genital warts, STIs often come back.

A doctor will usually recognize genital warts with the naked eye. He will check the anus and genital area for skin changes and may take a tissue sample, which will be examined under a microscope. Genital warts inside the body, such as in the rectum, vaginal lining, or urethra, are more difficult to detect. A special examination is often needed - an examination of the vagina, rectum, or urethra.

Once genital warts are identified, the surgeon may surgically remove the growths or freeze them with liquid nitrogen. Sometimes special creams and ointments are used. In rarer cases, when genital warts grow on the tongue or around the eyes, an ear, nose, and throat (ENT) specialist or an ophthalmologist can help.

The main features of preparations for papillomas

Salicylic acid preparations which, due to their keratolytic effect, reduce the mass of warts and sometimes also lead to scarring with continued use, are among the most common anti-wart preparations. Salicylic acid destroys the intercellular cohesion of corneal cells and thus dissolves hyperkeratosis.

Salicylates can be extensively absorbed through the skin and cause intoxication. Therefore, during pregnancy, babies and young children, as well as kidney failure, long-term treatment in large areas should be avoided. In addition, it avoids contact with eyes and mucous membranes. Medicines should not be applied to the genital area and face. As drugs vary considerably in salicylic acid concentration

To stop cell division, cytostatics are used locally in the treatment of warts. By inhibiting DNA and RNA synthesis, cytostatics prevent cell proliferation and therefore the spread of the virus.

Immunomodulators are approved for the treatment of external genital warts and perianal warts in adults.

Tool Selection Criteria

Benign growths usually regress when the immune system is able to kill the viruses on the skin. However, if warts are in the way, the following treatment options can be considered:

  • medicines;
  • cryotherapy;
  • surgical ablation.

To protect against human papillomavirus infection, attention should be paid to hygiene measures - disinfection of hands and feet, for example, in swimming pools. Vaccines have been available against papillomavirus types 6, 11, 16, and 18 since 2006. In addition to cervical cancer, papillomaviruses also cause external genital warts and vulvar skin lesions.

To reduce the risk of developing cervical cancer, the Permanent Commission on Vaccination (STIKO) at the Robert Koch Institute recommends vaccinating girls before first sexual intercourse (ages 9-14) in the 2018 vaccination recommendation. There is also scientific evidence that vaccinating pubertal boys, who are common carriers of the virus, can help control the spread of cervical cancer.

There are other ointments (eg oxolinic) whose clinical effectiveness has not been proven.

Salicylic ointment for papillomas is rarely used these days as it has a significant number of side effects. Several topical therapies are available for the treatment of external genital warts (Condylomata acuminata), and their effectiveness is difficult to assess because the success rates of studies on individual procedures vary widely. Not everything can prevent frequent relapses and cause significant local discomfort. There is no standard therapy.

Clinical trials are not available for comparison with other treatment options. Due to insufficient documentation, high spontaneous healing and significant side effects, the use of tea extract is not recommended.

Locally acting antipapillomatic drugs

Genital warts are caused by sexually transmitted human papillomaviruses, most often types 6 and 11. On the one hand, they can heal spontaneously, on the other hand, they overwhelm patients and very rarely degenerate into malignant tumors.

It is not recommended to take and apply any means without consulting a doctor. Which ointment is the best and most effective will tell the doctor.

Contraindications and side effects

In rarer cases, it can also lead to skin hypersensitivity reactions. If there is hypersensitivity to methyl 4-hydroxybenzoate or propyl 4-hydroxybenzoate, the use of ointments should be completely abandoned. It is strictly prohibited to use ointments during pregnancy or lactation.

Ointments can cause skin irritation, abrasions and irritation. This side effect is relatively common, but it is no cause for alarm. Ointments are also used in 3-day cycles. After 3 days of use, four days are followed by a break where the skin is restored.